Explore the Top 10 Milan Startups Advancing Industries

10 Top Milan Startups

1. AAVantgarde Bio – Gene Therapies
2. SellUp – Warehouse Movement Data Platform
3. Flyted – Aerial Topography Monitoring
4. Aliagrid – Energy Grids Operations Monitoring
5. CareGlance – Optical Coherence Tomography Systems
6. Maind Capital – AI-powered Mergers & Acquisitions (M&A)
7. Up2You – Carbon Footprint Calculation
8. ZeroVPN – Business Network Security
9. Adas Mobile Group – Advanced Driver Assistance Systems (ADAS)
10. Alesea – Inventory Management

Discovering the 10 Top Startups

This data is sourced from StartUs Insights’ Discovery Platform, which includes 4.7 million startups, scaleups, and tech companies worldwide. Filters like location, founding year, technology readiness, and employee count narrowed our list to 1362 emerging companies in Milan. From these, we selected 10 innovative startups based on funding information and a unique popularity metric called Signal Strength. Signal Strength gauges the influence of a company within the global innovation ecosystem. Let’s dive in!

1. AAVantgarde Bio

• Founding Year: 2021
• Industry: Pharma
• Technology: Gene Therapies

AAVantgarde Bio develops advanced gene therapy platforms AAV Dual Hybrid and AAV-Intein to tackle the challenges of limited DNA capacity in traditional viral vectors. AAV Dual Hybrid uses DNA recombination and AAV-Intein relies on protein trans-splicing to provide large genes directly to tissues and cells to make gene therapies for two inherited eye diseases, Usher syndrome type 1B and Stargardt disease.

2. SellUp

• Founding Year: 2021
• Industry: Logistics
• Technology: Warehouse Movement Data Platform

SellUp offers a cloud-based SaaS platform to optimize warehouse and sales management for the fashion industry. It connects brands and retailers to streamline inventory movement and provide real-time data analysis to reduce waste and maximize profitability. Further, it tracks, allocates, and shares stock information by integrating sales channels, including e-commerce, point of sale (PoS), and social media. Its features include automated stock management, peer-to-peer inventory sharing, and customizable dashboards for sales insights. This improves business operations and enhances decision-making.

3. Flyted

• Founding Year: 2020
• Industry: Cross-industry
• Technology: Aerial Topography Monitoring

Flyted provides advanced aerial topography monitoring solutions using unmanned aerial systems (UAS) and precision sensors to collect data on infrastructure and terrain. The company’s platform captures high-resolution geo-referenced data through technologies such as light detection and ranging (LiDAR) and photogrammetry to produce 3D digital twins, computer-aided design (CAD) models, and detailed topographic maps. Flyted’s system enables millimetric inspections and visual assessments of transport, telecom, and energy infrastructure while offering features like AI-powered automated inspections and multi-band sensors for structural analysis for real-time asset monitoring.

4. Aliagrid

• Founding Year: 2021
• Industry: Energy
• Technology: Energy Grids Operations Monitoring

Aliagrid’s solutions monitor and optimize energy grid operations for environmental impact reduction. It integrates proprietary IoT sensors at city gates and decompression stations to continuously track methane emissions to ensure low power consumption and scalability. The company’s platform processes data in real time and reconciles satellite-based methane detection with site-level sensor data to provide correct emission reports. Aliagrid’s design supports multiple grid measurements while including maintenance alerts and intrusion detection through an interface. This assists energy providers in reducing emissions and improving grid efficiency by leveraging AI-driven predictive tools.

5. CareGlance

• Founding Year: 2019
• Industry: Cross-industry
• Technology: Optical Coherence Tomography Systems

CareGlance offers tunable lasers and portable optical coherence tomography (OCT) systems customized for industry 4.0 applications. They utilize high-speed swept source OCT technology to enable real-time monitoring of industrial processes like additive manufacturing and laser welding. CareGlance’s portable OCT micromodule, based on monolithic and hybrid integration, provides 3D imaging for different materials. Thus, the company enhances process accuracy and efficiency with applications across industries including automotive, aviation, and manufacturing including inline monitoring and defect prevention.

6. Maind Capital

• Founding Year: 2022
• Industry: FinTech
• Technology: AI-powered Mergers & Acquisitions

Maind Capital provides an AI-powered platform that integrates blockchain and token rewards to enhance mergers and acquisitions (M&A), investments, and fundraising. It streamlines financial analysis and decision-making to enhance the efficiency of complex transactions. The platform’s blockchain infrastructure provides transparent, secure operations while enabling real-time data access and verification throughout the M&A process. Additionally, token rewards incentivize participation and build a collaborative investment ecosystem.

7. Up2You

• Founding Year: 2020
• Industry: Climate Tech
• Technology: Carbon Footprint Calculation

Up2You offers customized solutions CliMax, Choral, PlaNet and Registry to measure, reduce, and offset carbon footprint. CliMax calculates CO2 emissions and identifies reduction strategies, while Choral simplifies sustainability reporting by optimizing data collection and enhancing team collaboration. PlaNet engages employees with interactive sustainability challenges to build a positive corporate culture. The Registry platform uses blockchain to securely track carbon credits and ensure transparency. Up2You benefits businesses by improving environmental, social, and governance (ESG) performance, enhancing brand reputation, and creating a positive environmental impact by combining these tools for emission offsets.

8. ZeroVPN

• Founding Year: 2023
• Industry: Cross-industry
• Technology: Business Network Security

ZeroVPN offers zero trust network access security platform to enhance business network security. It secures digital environments by providing dedicated gateways, cloud firewall services, and smart remote access to maintain uninterrupted and secure connectivity. ZeroVPN simplifies complex cybersecurity with an interface that protects networks with features including management of network access, scalable protection across multiple devices, and real-time monitoring.

9. Adas Mobile Group

• Founding Year: 2021
• Industry: Automotive
• Technology: Advanced Driver Assistance Systems (ADAS)

Adas Mobile Group provides calibration services for ADAS such as front and rear cameras, radars, and surround view systems. The company provides technical and training support with an access to a proprietary platform, and a dedicated app to streamline service management. Adas Mobile Group’s network enables car repairers to stay updated with modern vehicle technologies while enhancing their service offerings and ensuring drivers’ safety on the road.

10. Alesea

• Founding Year: 2019
• Industry: Cross-industry
• Technology: Inventory Management

Alesea converts cable drums from simple packages into intelligent assets that enhance efficiency in inventory management and operations. Its system integrates sensored tracking devices with GPS, environmental sensors, and motion detectors to autonomously provide real-time data on asset location, status, usage, and handling conditions. This information accessed through a cloud-based platform offers insights and event notifications. Its features include automated data collection, periodic reporting for optimizing inventory levels, and consulting services to turn data into meaningful actions. The company reduces costs, improves service quality, and enhances asset management efficiency by streamlining operations.

Explore the Milan Startup Ecosystem

The Milan tech startups’ ecosystem comprises 1,362 companies with an average of 15 employees, indicating a landscape dominated by small and agile teams. Unique to this ecosystem is its strong presence in diverse industries such as fintech, manufacturing, food and beverages, apparel and fashion, and healthcare. This diversity fosters cross-industry innovation, creating opportunities for collaboration and technology transfer between sectors.

Key investors include CDP Venture Capital, Polytechnic University of Milan, 360 Capital, Azimut Libera Impresa and B4i Bocconi for Innovation. They showcase a support network from academic institutions and venture capital with funding stages such as seed, early stage VC, and pre-seed to highlight early-stage development and position the ecosystem as an environment for building new ideas and growth for startups and corporates alike.

This is just the tip of the iceberg. For personalized insights into the local or global startup ecosystem, depending on your needs, get in touch with us. We can provide tailored information and analysis to help you navigate the vibrant startup landscape.