Neurological enhancement startups are revolutionizing various industries as innovative startups harness the power of the brain to create groundbreaking solutions. From healthcare and education to gaming and productivity, these companies are developing cutting-edge applications that tap into our cognitive potential.
Brain-computer interfaces, neurofeedback systems, and non-invasive stimulation techniques are being employed to treat neurological disorders, boost learning capabilities, enhance athletic performance, and even control devices with thought alone. In the workplace, neurotech startups are exploring ways to improve focus, creativity, and decision-making.
The military and aerospace sectors are also investigating neural enhancement for heightened situational awareness and faster reaction times. As these technologies continue to evolve, they promise to reshape our understanding of human potential and open up new frontiers in personal and professional development, raising both excitement and ethical considerations about the future of human cognition
5 Neurological Enhancement Startups to Watch in 2025
- MYNERVA – AI-powered neuroprosthetic
- SparshMind Innovations – VR-based telerehabilitation
- Neuphoria – Advanced Biohacking
- SPIRE Therapeutics – Deep brain therapy
- MindsApplied – Neuroscience as a Service
Global Startup Heat Map highlights 5 Neurological Enhancement Startups to Watch
Through the Big Data & Artificial Intelligence (AI)-powered StartUs Insights Discovery Platform, covering over 4 760 120+ startups & scaleups globally, we identified 54 neurological enhancement startups.
The Global Startup Heat Map below highlights the 5 neurological enhancement startups you should watch in 2025 as well as the geo-distribution of all neurological enhancement startups & scaleups we analyzed for this research.
Based on the heat map, we see high startup activity in London. Cambridge, Houston, San Diego, Los Angeles.
Explore 5 Neurological Enhancement Startups to Watch in 2025
We hand-picked startups to showcase in this report by filtering for their technology, founding year, location, funding, and other metrics. These neurological enhancement startups work on solutions ranging from diabetic treatment to neurological disorders, and neural data interpretation, and more.
1. MyNerva
- Founding Year: 2023
- Location: Zurich, Switzerland
- Solution: Treating Diabetic Neuropathy
MyNerva develops Leia, an AI-powered neuroprosthetic sock for treating diabetic neuropathy. The company’s product combines non-invasive electrical pulses with artificial intelligence to reduce pain and improve mobility for patients.
Leia features a comfortable, wearable design that integrates into daily routines. The sock incorporates a pressure-capturing sole with embedded sensors that collect real-time data.
A control unit processes this information using AI-driven algorithms by translating it into gentle electrical pulses delivered through electrodes. MYNERVA’s technology addresses both pain reduction and fall prevention.
2. SparshMind Innovations
- Founding Year: 2023
- Location: New Delhi, India
- Solution: Neurological Disorders
SparshMind Innovations provides VR-based telerehabilitation systems designed to address neurological disorders. Its technology integrates virtual reality with artificial intelligence to provide personalized therapy tailored to each patient’s recovery needs.
Its ReMind Neuro is designed to target neuroplasticity and suppress maladaptive behavior using insights from evidence-based protocols like CIMT (Constraint-Induced Movement Therapy), ADL (Activities of Daily Living), and Mirror neuron activation into an automated platform.
This system employs advanced neuroplasticity principles that allow users to engage in immersive exercises that target motor, sensory, and cognitive functions. It offers real-time patient data analysis for adaptive feedback for improved rehabilitation process. The company focuses on improving accessibility, enabling remote monitoring, and delivering effective therapy beyond traditional clinical settings.
3. Neuphoria
- Founding Year: 2023
- Location: Brisbane, Australia
- Solution: Mental Performance and Well-Being
Neuphoria offers biohacking solutions leveraging neurofeedback technology to enhance mental performance and well-being. Its product integrates advanced EEG sensors with brainwave training programs for stress reduction, productivity, and cognitive optimization.
The technology incorporates a wearable headband equipped with silver oxide fabric sensors and lithium-ion batteries that offer 12-hour usability for extended sessions.
The company’s solutions utilize two-channel EEG systems to monitor brain activity and provide real-time neurofeedback through tailored protocols. It provides personalized neurofeedback training and AI-powered recommendations for peak performance, achieving flow state, enhanced focus, and creativity.
4. SPIRE Therapeutics
- Founding Year: 2023
- Location: Salt Lake City, USA
- Solution: Neurological Disorder Treatment
SPIRE Therapeutics develops Diadem, a noninvasive deep brain therapy device utilizing ultrasonic neuromodulation to treat major depression and other neurological conditions. It employs controlled, low-intensity ultrasound waves delivered through transcranial arrays that electronically focus sound waves.
The company’s proprietary techniques enable effective drug delivery and neuromodulation through the skull by applying specific corrections, such as the Relative Through-Transmit (RTT) method. This approach facilitates the release of encapsulated therapeutic agents, enhancing clinical outcomes by allowing dose-specific, localized treatments.
SPIRE Therapeutics’ innovations demonstrate efficacy in controlled nerve stimulation and therapeutic modulation by leveraging biocompatible nanoparticle carriers for targeted drug release. Its non-invasive alternative provides patients with safer, scalable, and efficient solutions for addressing neurological disorders.
5. MindsApplied
- Founding Year: 2023
- Location: Los Angeles, United States
- Solution: Advanced Neural Data Interpretation
MindsApplied develops Neuroscience-as-a-Service solutions that integrate brain-computer interface (BCI) technologies for advanced neural data interpretation. Its platform enables users to train predictive models based on neural activity.
Its Cognichat leverages thought-to-text prediction by combining natural language processing with calibrated inner speech for communication. Cognitrol applies motor imagery and directional neural patterns to control virtual environments.
The company aims to enhance accessibility and user interaction by tailoring neural technology for healthcare, gaming, and communication sectors, providing innovative tools for practical brain-computer interfacing.
Discover All Emerging Healthcare Startups
The healthcare startups showcased in this report are only a small sample of all startups we identified through our data-driven startup scouting approach. Download our free Healthcare Innovation Report for a broad overview of the industry or get in touch for quick & exhaustive research on the latest technologies & emerging solutions that will impact your company in 2025!
